Will be in Lacrosse to visit the in-laws but wil have some time to wet a line. Love the river and its backwater. but I am looking for particulars to make my limited time productive.

I would be hitting the upstream side of the wingdams, and upstream sides of islands.  I would stay in the main or secondary channels, and not waste much time with the slower water.

There is plenty of good fishing around the area where the LaCrosse river flows into the old miss.

How is that?  

More?

Use some jigs, soft plastics, or even troll some crankbaits along the RR tracks.