Early May Fishing Trip

This coming May, me and a buddy will be taking a two week trip with the goal of catching as many trout and smallmouth as possible, not too concerned with largemouth as we can catch those anytime we want down here.  We will likely be camping to save money, and would like to hit around two or three states that way we can see some different scenery without wasting our trip driving around (and of course the fishing matters much more than the scenery.)  If it makes a difference, trout will be done exclusively on the fly rod, we'll probablly start with conventional tackle on the smallmouth but once we've caught a few the fly rods will be coming out for them as well.

Is there anywhere that we just have to hit, any pointers for making a trip like this, etc.?  Any suggestions would be greatly appreciated.