I was looking at a reel primarily for swimbaits.  Which would be a better way to go, a 300 or 400 series calcutta.  And also would you think that a Daiwa Luna 253 would be ok with lures in the 1-4 oz. range.

for 1 to 4 oz lures, I wouldn't go out and buy anything special. If you have a quality reel with a low say 5:3 or lower gear ratio, you should do fine.

My main focus would be on the rod.

agree with avid.

nothing special is NECESSARY but a curado 300 would be SWEET!!!!

For bigger baits, calcutta 400.

I recently bought an Okuma big bait rod, 7'6" MH, and I am waiting for Cabela's to send that Revo STX I want to put on it. Is this a good reel for this rod? None of my swimbaits weigh more than 2 ozs. yet. If the ratio is that important, I'll turn the STX into a c-rig/light pitching reel, and try a CU300 or other reel for swimbaitin'.

I fish the Hudds and BBZ with a Cardiff 301, I've never felt the need of a bigger reel, you should check it out. Size is weight