Great question!
No, lizards are not just for spring. However, in spring, they really do shine.
When I fish a C-rig, I want a lure that is going to look large, so, I would use 8 in. lizards, 10-12 inc. worms, etc.
If you find that the fish are not reacting to that, go to smaller versions of these lures.
If they are not reacting to regular worms, or lizards, then, try Senkos, or Sweebo worms.
Also, do not be afraid to fish the creature baits on a C-rig. Especially if you have a strong forage bass of crawfish, use the creature baits.
Hope that this give you some insight. Oh yeah, and for this time of year, I fish large lizards 8 in. or larger, and I will also fish creature baits.