That would have nothing to do with uphill or downhill. Why are you toiling over this? What ever you figure out today may not be true tomorrow, or five minutes from now.

Fish where the fish are, use baits that get to the fish, try different profiles, speeds, and finally colors until a pattern develops. That past few threads, you're over thinking.

So in other words.....Sure, try a worm instead. 

Or don't? It's not going to help. These aren't problems that every single person doesn't face every moment on the water. It can only be solved by fishing. It's not like line twist, break offs, or a new rig that you can correct and apply next time. Today, uphill with a black worm. Tomorrow downhill with a jig. Next tuesday, a flat a mile away on a topwater at dusk. To answer your question, yes, try a jig uphill. Maybe you'll catch a fish.

Or don't? It's not going to help. These aren't problems that every single person doesn't face every moment on the water. It can only be solved by fishing. It's not like line twist, break offs, or a new rig that you can correct and apply next time. Today, uphill with a black worm. Tomorrow downhill with a jig. Next tuesday, a flat a mile away on a topwater at dusk. To answer your question, yes, try a jig uphill. Maybe you'll catch a fish

Uhhh...okay.   Arent you kinda over thinking this a little bit.

I don't think anyone is overthinking, just trying to help. The simple answer to your original post was/ is; there are times when working uphill will produce and the direction of the retrieve has little bearing on whether or not you hang up, the style of the jig does.