Hey guys in a couple weekends will be headed down towards the Potomac river targeting Muskie and Pike. Now I know big spinnerbait and spoons are ideal for this type of fishing but anyone have an idea as to where they may be? Any tips be appreciated 

Try and target bass... a pike is sure to come hit your lure.  

Find the bait and the skis & pike will be nearby. Don't forget that they will eat bass too.

Southeast Georgian Bay Where Monster Muskies Lurk

More muskies are caught in this area of Georgian Bay, particularly the Moon River basin and Honey Harbor, than anywhere else. It's not that these are the only river mouth areas that are good, although both these spots have massive spawning flats that draw hundreds of big muskie back each year, but their proximity to large metropolitan areas makes them extra attractive. Casting bucktails (often deep) is the most productive summer tactic. Numerous big muskie are caught on Lindy Hot Spot and Muskie Roller bucktails, along with BucherTails, Mepps and a few local brands. Top colors are black/silver blade, black/chartreuse or purple/orange. This location would be my choice for Muskies.

http://www.boats.com/where-monster-muskies-lurk/

Make them angry

Even though pike and muskies are both from the esox family, muskies are usually bigger, and they are MUCH harder to catch.  I sometimes catch 40-50 pike a trip on accident when I'm bass fishing and I haven't caught a muskie in 15 years.  Sometimes its almost impossible to get the lures past pike to get to the bass!  One thing I would do is upsize your presentation.  Throw some BIG muskie lures and that will at least reduce the unwanted catches of smaller pike which are notoriously aggressive.

Well here in Mo. the muskie seem to like Rat-l-traps.

 

4 hours ago, Hot Rod Johnson said:

 Yes I would bet that Pomme de Terre Reservoir will most likely turn on in between the 12th and 19th of October...The water temperatures and the Full Moon which is on the 16th this year should be the "Fall Peak Fishing Period". Yes! A "Rattle Trap" will play big during this time frame and they definitely work. I would stick with the 3/4 oz, and the 1 oz. traps. You want to fish them as fast as possible with a high speed reel because you are looking for more of a "Reaction Strike"... Rattle Traps can cover allot of water and many different depts. Just have to play with the colors... (i.e.) "Shad Colors", and try to locate the "Suspending Fish" that occupy Lake Pomme de Terre Reservoir... They may be located 20 to 30 feet deep where small shad are located.

I "really" am "confused" by this bit of "information".

3 minutes ago, everythingthatswims said:

I "really" am "confused" by this bit of "information".

LOL, Me also because I posted it in the incorrect thread. I will have to see how I can correct my error, thanks for the heads up..

Look for Pike in the slack water and eddys, under overhanging trees, and other cover.

I've never seen or caught a Northern Pike in the Upper Potomac River, but I have caught Muskies while fishing for smallmouth bass.  Last Sunday I hooked into a 10-inch smallmouth and after it jumped twice a 40+ inch Muskie tried to grab it twice!  First time that's happened to me!!!

So here's my tip:  Go smallmouth fishing and just play them a little longer than normal...