So i bought a 7ft med lt, fast action rod with the intention of throwing light bucktails and marabou jigs with it. I wanted to use 2/8 braid with a long leader on it to maximize feel and casting distance. I didnt realize it has microguides though. I’m concerned my fg or alberto leader know is going to negate the casting distance gains i was getting using light braid. Should i throw a light fluro instead or just deal with the braid to leader knot contacting my microguides? Not sure what is best way to go here.

If you are good at the knots and they are nice and small it shouldn't make a noticeable difference. 

Most of my rods have micro guides.

"Micro" covers a range of guide sizes so It's hard to say for certain, but your line is really light so I wouldn't expect any problem. You also skipped an option, straight braid. I use it all the time in very clear water with no problem.

Measure the inside diameter of the guides.  4.5 mm will work just fine with an FG knot on 50 lb braid and 20 lb leader so should be fine for your application.

 

If you are talking true micro, you'd probably still be fine as long as you down size the line.  Bigger line would be a broble.  I'd give it a whirl and see what happens.

Try a short leader. 10” to 2’ - If it only hits the top 2-3 guides, you should be good to go. Try tying an overhand knot in the leader (8-10lb or less) with as small a tag as possible to a uni in the thinner braid. Fits through guides good, won’t break on a fish, but is weak on a snag. That’s what I do.

I use micro guides and leaders on my spinning rods often, no issues, just tie a good knot and you're good.