Pike are my favorite fish, and like @Scott F, I've caught thousands, on both conventional gear and flies.
Oddly enough, I don't target them much, as it's easy enough to get them when we're targeting smallies ans muskies. This year's biggest was in the mid-30s.
I don't lose a lot of lures to them, because I run tieable wire leaders on almost everything except cheap soft plastics.
We had a comical incident this year: We took a guy who is mostly a trout angler on a smallie/musky float. Even though we told him to, he didn't bother to tie wire in on the red/white bucktail popper he'd made for the trip...and on his first cast, he twitched it once...and it disappeared in a big swirl...and his line went slack. He just sat there, mouth open...and we laughed. 10 seconds later the popper floated to the surface...I tossed a properly rigged (12" 13# tieable wire leader) popper into the same spot, and it got clobbered on the 3rd or 4th pop...and a nice high 20's pike hit the net.
Then we rowed in and got his popper, and handed it to him with the spool of wire...
...on the 50# fluoro mentioned above: Tieable wire works better, and is at least as flexible...and I've seen 50# and 60# fluoro cut like it wasn't there...and the fish that did it were not all big. I saw a monster musky lost because of a 50# fluoro leader once...I avoided saying "I told you so." If someone could convince my esox were line shy, the absolute smallest size I'd consider would be 80#...and that stuff kills lure/fly action.
LOTW 38, on the fly.